Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FGD3FYVE, RhoGEF and PH domain containing 3. (1183 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
    
 0.981
GNG12
G protein subunit gamma 12.
     
 0.905
FGD4
FYVE, RhoGEF and PH domain containing 4.
    
 0.657
ITSN2
Intersectin 2.
     
 0.560
ITSN1
Intersectin 1.
     
 0.545
ARHGEF12
Rho guanine nucleotide exchange factor 12.
    
 0.526
ARHGEF11
Rho guanine nucleotide exchange factor 11.
    
 0.526
ARHGEF33
Rho guanine nucleotide exchange factor 33.
     
 0.518
DOCK8
Dedicator of cytokinesis 8.
   
 
 0.512
WIPF1
WAS/WASL interacting protein family member 1.
      
 0.476
Your Current Organism:
Phasianus colchicus
NCBI taxonomy Id: 9054
Other names: P. colchicus, Ring-necked pheasant, common pheasant
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