Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
INSIG1Insulin induced gene 1. (247 aa)    
Predicted Functional Partners:
SCAP
SREBF chaperone.
    
 0.932
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase.
   
 
 0.920
CHAF1B
Chromatin assembly factor 1 subunit B.
    
 
 0.809
PCNA
Proliferating cell nuclear antigen.
    
 
 0.759
ENSPCLP00000016642
annotation not available
   
 
 0.746
RNF139
Ring finger protein 139.
    
 
 0.717
FAF2
Fas associated factor family member 2.
    
 
 0.709
AMFR
Autocrine motility factor receptor.
    
 
 0.698
ASF1A
Anti-silencing function 1A histone chaperone.
   
 
 0.690
HIRA
Histone cell cycle regulator.
    
 
 0.642
Your Current Organism:
Phasianus colchicus
NCBI taxonomy Id: 9054
Other names: P. colchicus, Ring-necked pheasant, common pheasant
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