Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (487 aa)    
Predicted Functional Partners:
TNIP2
TNFAIP3 interacting protein 2.
   
 0.999
NFKB1
Nuclear factor kappa B subunit 1.
   
 0.996
MAP3K14
Mitogen-activated protein kinase kinase kinase 14.
    
0.995
MAP2K1
Mitogen-activated protein kinase kinase 1.
  
 
0.979
ENSPCLP00000017974
annotation not available
  
 
0.979
NFKB2
Nuclear factor kappa B subunit 2.
   
 0.966
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
0.962
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
    
0.956
ENSPCLP00000009813
annotation not available
   
 0.765
REL
REL proto-oncogene, NF-kB subunit.
   
 
 0.724
Your Current Organism:
Phasianus colchicus
NCBI taxonomy Id: 9054
Other names: P. colchicus, Ring-necked pheasant, common pheasant
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