MKX protein (Phasianus colchicus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

MKX

Mohawk homeobox. (350 aa)

Predicted Functional Partners:

IRX1

0.857

IRX4

0.854

TNMD

0.790

HOXC9

0.627

HOXC4

0.597

MEOX2

0.590

DCN

0.585

ENSPCLP00000012810

0.582

KNTC1

0.566

SCX

0.563

Your Current Organism:

Phasianus colchicus

NCBI taxonomy Id: 9054
Other names: P. colchicus, Ring-necked pheasant, common pheasant

Export your current network:

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same PNG format, but at higher resolution

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCN	MKX	ENSPCLP00000011419	ENSPCLP00000001308	Decorin.	Mohawk homeobox.	0.585
DCN	TNMD	ENSPCLP00000011419	ENSPCLP00000007527	Decorin.	Tenomodulin.	0.729
ENSPCLP00000012810	IRX1	ENSPCLP00000012810	ENSPCLP00000003328	annotation not available	Iroquois homeobox 1.	0.580
ENSPCLP00000012810	IRX4	ENSPCLP00000012810	ENSPCLP00000003343	annotation not available	Iroquois homeobox 4.	0.443
ENSPCLP00000012810	MKX	ENSPCLP00000012810	ENSPCLP00000001308	annotation not available	Mohawk homeobox.	0.582
HOXC4	HOXC9	ENSPCLP00000012172	ENSPCLP00000012162	Homeobox C4.	Homeobox C9.	0.678
HOXC4	MKX	ENSPCLP00000012172	ENSPCLP00000001308	Homeobox C4.	Mohawk homeobox.	0.597
HOXC9	HOXC4	ENSPCLP00000012162	ENSPCLP00000012172	Homeobox C9.	Homeobox C4.	0.678
HOXC9	MKX	ENSPCLP00000012162	ENSPCLP00000001308	Homeobox C9.	Mohawk homeobox.	0.627
IRX1	ENSPCLP00000012810	ENSPCLP00000003328	ENSPCLP00000012810	Iroquois homeobox 1.	annotation not available	0.580
IRX1	IRX4	ENSPCLP00000003328	ENSPCLP00000003343	Iroquois homeobox 1.	Iroquois homeobox 4.	0.911
IRX1	MKX	ENSPCLP00000003328	ENSPCLP00000001308	Iroquois homeobox 1.	Mohawk homeobox.	0.857
IRX4	ENSPCLP00000012810	ENSPCLP00000003343	ENSPCLP00000012810	Iroquois homeobox 4.	annotation not available	0.443
IRX4	IRX1	ENSPCLP00000003343	ENSPCLP00000003328	Iroquois homeobox 4.	Iroquois homeobox 1.	0.911
IRX4	MKX	ENSPCLP00000003343	ENSPCLP00000001308	Iroquois homeobox 4.	Mohawk homeobox.	0.854
KNTC1	MKX	ENSPCLP00000004922	ENSPCLP00000001308	Kinetochore associated 1.	Mohawk homeobox.	0.566
MEOX2	MKX	ENSPCLP00000004944	ENSPCLP00000001308	Mesenchyme homeobox 2.	Mohawk homeobox.	0.590
MKX	DCN	ENSPCLP00000001308	ENSPCLP00000011419	Mohawk homeobox.	Decorin.	0.585
MKX	ENSPCLP00000012810	ENSPCLP00000001308	ENSPCLP00000012810	Mohawk homeobox.	annotation not available	0.582
MKX	HOXC4	ENSPCLP00000001308	ENSPCLP00000012172	Mohawk homeobox.	Homeobox C4.	0.597