Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SRD5A2Steroid 5 alpha-reductase 2. (251 aa)    
Predicted Functional Partners:
SRD5A3
Steroid 5 alpha-reductase 3.
     
 0.953
HSD17B3
Hydroxysteroid 17-beta dehydrogenase 3.
     
 0.942
CYP17A1
Cytochrome P450 family 17 subfamily A member 1.
     
 0.938
CYP19A1
Cytochrome P450 family 19 subfamily A member 1.
     
 0.937
HSD17B2
Hydroxysteroid 17-beta dehydrogenase 2.
     
 0.932
AKR1D1
Aldo-keto reductase family 1 member D1.
     
 0.930
ENSPCLP00000024215
annotation not available
     
 0.930
ENSPCLP00000021578
annotation not available
     
 0.921
SRD5A1
Steroid 5 alpha-reductase 1.
  
  
 
0.905
ENSPCLP00000018345
annotation not available
     
 0.900
Your Current Organism:
Phasianus colchicus
NCBI taxonomy Id: 9054
Other names: P. colchicus, Ring-necked pheasant, common pheasant
Server load: low (20%) [HD]