Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
HERC1HECT and RLD domain containing E3 ubiquitin protein ligase family member 1. (4861 aa)    
Predicted Functional Partners:
RNF8
Ring finger protein 8.
   
 0.924
UBE3A
Ubiquitin protein ligase E3A.
   
 0.867
BRCA1
BRCA1 DNA repair associated.
    
 0.846
NCOA4
Nuclear receptor coactivator 4.
    
 
 0.801
MAPK6
Mitogen-activated protein kinase 6.
    
 
 0.800
RPA1
Replication protein A1.
    
   0.771
CEP170
Centrosomal protein 170.
    
 
 0.763
USP16
Ubiquitin specific peptidase 16.
    
 
 0.743
USP38
Ubiquitin specific peptidase 38.
    
   0.742
FBXL5
F-box and leucine rich repeat protein 5.
    
 
 0.711
Your Current Organism:
Phasianus colchicus
NCBI taxonomy Id: 9054
Other names: P. colchicus, Ring-necked pheasant, common pheasant
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