Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RNF8Ring finger protein 8. (523 aa)    
Predicted Functional Partners:
ENSPCLP00000011369
annotation not available
   
 0.995
RNF168
Ring finger protein 168.
     
 0.951
TP53BP1
Tumor protein p53 binding protein 1.
    
 0.949
PCNA
Proliferating cell nuclear antigen.
    
 
 0.942
PAXIP1
PAX interacting protein 1.
    
 0.935
ENSPCLP00000016676
annotation not available
    
 0.935
HERC1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1.
   
 0.924
HERC2
HECT and RLD domain containing E3 ubiquitin protein ligase 2.
   
 0.924
CLYBL
Citrate lyase beta like.
   
   0.882
UBE2V2
Ubiquitin conjugating enzyme E2 V2.
   
 0.876
Your Current Organism:
Phasianus colchicus
NCBI taxonomy Id: 9054
Other names: P. colchicus, Ring-necked pheasant, common pheasant
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