Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SIX2SIX homeobox 2. (287 aa)    
Predicted Functional Partners:
EYA1
EYA transcriptional coactivator and phosphatase 1.
    
 0.860
EYA2
EYA transcriptional coactivator and phosphatase 2.
    
 0.815
EYA4
EYA transcriptional coactivator and phosphatase 4.
    
 0.754
EYA3
EYA transcriptional coactivator and phosphatase 3.
    
 0.711
PAX2
Paired box 2.
     
 0.691
WT1
WT1 transcription factor.
    
 
 0.585
SALL1
Spalt like transcription factor 1.
     
 0.581
HOXD11
Homeobox D11.
     
 0.565
HOXB7
Homeobox B7.
    
 
 0.564
WNT9B
Wnt family member 9B.
      
 0.555
Your Current Organism:
Phasianus colchicus
NCBI taxonomy Id: 9054
Other names: P. colchicus, Ring-necked pheasant, common pheasant
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