Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHH2Pleckstrin homology, MyTH4 and FERM domain containing H2. (1502 aa)    
Predicted Functional Partners:
PLEKHG1
Pleckstrin homology and RhoGEF domain containing G1.
      
 0.558
AREL1
Apoptosis resistant E3 ubiquitin protein ligase 1.
      
 0.558
SNX29
Sorting nexin 29.
      
 0.556
SHISA3
Shisa family member 3.
      
 0.554
NOP53
NOP53 ribosome biogenesis factor.
      
 0.485
UNC5D
Unc-5 netrin receptor D.
    
 
 0.464
UNC5C
Unc-5 netrin receptor C.
    
 
 0.464
ENSPCLP00000023467
annotation not available
      
 0.451
PLEKHF2
Pleckstrin homology and FYVE domain containing 2.
      
 0.450
RFC3
Replication factor C subunit 3.
      
 0.449
Your Current Organism:
Phasianus colchicus
NCBI taxonomy Id: 9054
Other names: P. colchicus, Ring-necked pheasant, common pheasant
Server load: low (32%) [HD]