Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PARP1poly(ADP-ribose) polymerase 1. (1009 aa)    
Predicted Functional Partners:
PARG
poly(ADP-ribose) glycohydrolase.
    
 0.998
CASP7
Caspase 7.
    
 0.997
PARP3
poly(ADP-ribose) polymerase family member 3.
  
 
0.997
CASP3
Caspase 3.
    
 0.996
POLB
DNA polymerase beta.
    
 0.994
CHD1L
Chromodomain helicase DNA binding protein 1 like.
    
 0.994
PCNA
Proliferating cell nuclear antigen.
   
 0.993
XPC
XPC complex subunit, DNA damage recognition and repair factor.
    
 0.992
APLF
Aprataxin and PNKP like factor.
    
 
 0.990
XRCC6
X-ray repair cross complementing 6.
   
 
 0.990
Your Current Organism:
Phasianus colchicus
NCBI taxonomy Id: 9054
Other names: P. colchicus, Ring-necked pheasant, common pheasant
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