STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HIC1HIC ZBTB transcriptional repressor 1. (665 aa)    
Predicted Functional Partners:
SIRT1
Sirtuin 1.
    
 0.630
TOP1
DNA topoisomerase I.
    
 
 0.573
IRS1
Insulin receptor substrate 1.
  
 
 0.569
MAN1B1
Mannosidase alpha class 1B member 1.
      
 0.559
MYSM1
Myb like, SWIRM and MPN domains 1.
    
  0.471
FOXO1
Forkhead box O1.
    
 
 0.464
UBE2I
Ubiquitin conjugating enzyme E2 I.
    
  0.456
CTBP1
C-terminal binding protein 1.
    
 
 0.443
CTBP2
C-terminal binding protein 2.
    
 
 0.443
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
  0.439
Your Current Organism:
Phasianus colchicus
NCBI taxonomy Id: 9054
Other names: P. colchicus, Ring-necked pheasant, common pheasant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.