Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1159 aa)    
Predicted Functional Partners:
TEK
TEK receptor tyrosine kinase.
   
 
 0.962
MUSK
Muscle associated receptor tyrosine kinase.
   
  0.931
ANGPT2
Angiopoietin 2.
   
 0.906
ANGPT1
Angiopoietin 1.
    
 0.856
ANGPT4
Angiopoietin 4.
    
 0.847
PDGFC
Platelet derived growth factor C.
    
 
 0.828
CDH5
Cadherin 5.
   
 
 0.803
DOK2
Docking protein 2.
    
 0.733
GRB2
Growth factor receptor bound protein 2.
    
 0.693
NOS2
Nitric oxide synthase 2.
   
  
 0.687
Your Current Organism:
Phasianus colchicus
NCBI taxonomy Id: 9054
Other names: P. colchicus, Ring-necked pheasant, common pheasant
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