STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALDH22A1Aldehyde dehydrogenase 22A1; Belongs to the aldehyde dehydrogenase family. (595 aa)    
Predicted Functional Partners:
P5CS
Delta-1-pyrroline-5-carboxylate synthase; P5CS plays a key role in proline biosynthesis, leading to osmoregulation in plants; In the N-terminal section; belongs to the glutamate 5- kinase family.
  
 
 0.719
MA16_Dca015610
Putative 3-hydroxyisobutyrate dehydrogenase, mitochondrial.
  
 0.717
MA16_Dca017821
Putative acetyl-CoA acetyltransferase, cytosolic 2; Belongs to the thiolase-like superfamily. Thiolase family.
   
 
 0.612
MA16_Dca011395
Alcohol dehydrogenase-like 6.
  
 0.606
MA16_Dca025484
Uncharacterized protein.
  
 
 0.595
SCOA
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.595
AAE17
Putative acyl-activating enzyme 17, peroxisomal.
  
 
 0.577
ACS
Acetyl-coenzyme A synthetase.
  
 
 0.577
MED13
Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
  
 
 0.577
AAE18
Putative acyl-activating enzyme 18, peroxisomal.
  
 
 0.577
Your Current Organism:
Dendrobium catenatum
NCBI taxonomy Id: 906689
Other names: D. catenatum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.