GA3OX4-2 protein (Dendrobium catenatum) - STRING interaction network

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second shell of interactors

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Edges:

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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Score

GA3OX4-2

Gibberellin 3-beta-dioxygenase 4; Belongs to the iron/ascorbate-dependent oxidoreductase family. (324 aa)

Predicted Functional Partners:

GA3OX3-3

0.562

SWEET4

0.513

SWEET4-3

0.513

SWEET4-4

0.513

SWEET4-5

0.513

SWEET6B-3

0.513

SWEET7B-2

0.513

SWEET7B-3

0.513

RHA2B

0.512

ROMT

0.512

Your Current Organism:

Dendrobium catenatum

NCBI taxonomy Id: 906689
Other names: D. catenatum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GA3OX3-3	GA3OX4-2	A0A2I0WZL6	A0A2I0WGR3	Gibberellin 3-beta-dioxygenase 3.	Gibberellin 3-beta-dioxygenase 4; Belongs to the iron/ascorbate-dependent oxidoreductase family.	0.562
GA3OX4-2	GA3OX3-3	A0A2I0WGR3	A0A2I0WZL6	Gibberellin 3-beta-dioxygenase 4; Belongs to the iron/ascorbate-dependent oxidoreductase family.	Gibberellin 3-beta-dioxygenase 3.	0.562
GA3OX4-2	RHA2B	A0A2I0WGR3	A0A2I0V915	Gibberellin 3-beta-dioxygenase 4; Belongs to the iron/ascorbate-dependent oxidoreductase family.	Putative E3 ubiquitin-protein ligase RHA2B.	0.512
GA3OX4-2	ROMT	A0A2I0WGR3	A0A2I0VY66	Gibberellin 3-beta-dioxygenase 4; Belongs to the iron/ascorbate-dependent oxidoreductase family.	Trans-resveratrol di-O-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.	0.512
GA3OX4-2	SWEET4	A0A2I0WGR3	A0A2I0VIV9	Gibberellin 3-beta-dioxygenase 4; Belongs to the iron/ascorbate-dependent oxidoreductase family.	Bidirectional sugar transporter SWEET; Mediates both low-affinity uptake and efflux of sugar across the membrane; Belongs to the SWEET sugar transporter family.	0.513
GA3OX4-2	SWEET4-3	A0A2I0WGR3	A0A2I0VIW2	Gibberellin 3-beta-dioxygenase 4; Belongs to the iron/ascorbate-dependent oxidoreductase family.	Bidirectional sugar transporter SWEET; Mediates both low-affinity uptake and efflux of sugar across the membrane; Belongs to the SWEET sugar transporter family.	0.513
GA3OX4-2	SWEET4-4	A0A2I0WGR3	A0A2I0VIW6	Gibberellin 3-beta-dioxygenase 4; Belongs to the iron/ascorbate-dependent oxidoreductase family.	Bidirectional sugar transporter SWEET; Mediates both low-affinity uptake and efflux of sugar across the membrane; Belongs to the SWEET sugar transporter family.	0.513
GA3OX4-2	SWEET4-5	A0A2I0WGR3	A0A2I0VIY1	Gibberellin 3-beta-dioxygenase 4; Belongs to the iron/ascorbate-dependent oxidoreductase family.	Bidirectional sugar transporter SWEET; Mediates both low-affinity uptake and efflux of sugar across the membrane; Belongs to the SWEET sugar transporter family.	0.513
GA3OX4-2	SWEET6B-3	A0A2I0WGR3	A0A2I0VQL5	Gibberellin 3-beta-dioxygenase 4; Belongs to the iron/ascorbate-dependent oxidoreductase family.	Bidirectional sugar transporter SWEET6b.	0.513
GA3OX4-2	SWEET7B-2	A0A2I0WGR3	A0A2I0VQM2	Gibberellin 3-beta-dioxygenase 4; Belongs to the iron/ascorbate-dependent oxidoreductase family.	Bidirectional sugar transporter SWEET; Mediates both low-affinity uptake and efflux of sugar across the membrane; Belongs to the SWEET sugar transporter family.	0.513
GA3OX4-2	SWEET7B-3	A0A2I0WGR3	A0A2I0VQN1	Gibberellin 3-beta-dioxygenase 4; Belongs to the iron/ascorbate-dependent oxidoreductase family.	Bidirectional sugar transporter SWEET; Mediates both low-affinity uptake and efflux of sugar across the membrane; Belongs to the SWEET sugar transporter family.	0.513
RHA2B	GA3OX4-2	A0A2I0V915	A0A2I0WGR3	Putative E3 ubiquitin-protein ligase RHA2B.	Gibberellin 3-beta-dioxygenase 4; Belongs to the iron/ascorbate-dependent oxidoreductase family.	0.512
RHA2B	ROMT	A0A2I0V915	A0A2I0VY66	Putative E3 ubiquitin-protein ligase RHA2B.	Trans-resveratrol di-O-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.	0.513
RHA2B	SWEET4	A0A2I0V915	A0A2I0VIV9	Putative E3 ubiquitin-protein ligase RHA2B.	Bidirectional sugar transporter SWEET; Mediates both low-affinity uptake and efflux of sugar across the membrane; Belongs to the SWEET sugar transporter family.	0.514
RHA2B	SWEET4-3	A0A2I0V915	A0A2I0VIW2	Putative E3 ubiquitin-protein ligase RHA2B.	Bidirectional sugar transporter SWEET; Mediates both low-affinity uptake and efflux of sugar across the membrane; Belongs to the SWEET sugar transporter family.	0.514
RHA2B	SWEET4-4	A0A2I0V915	A0A2I0VIW6	Putative E3 ubiquitin-protein ligase RHA2B.	Bidirectional sugar transporter SWEET; Mediates both low-affinity uptake and efflux of sugar across the membrane; Belongs to the SWEET sugar transporter family.	0.514
RHA2B	SWEET4-5	A0A2I0V915	A0A2I0VIY1	Putative E3 ubiquitin-protein ligase RHA2B.	Bidirectional sugar transporter SWEET; Mediates both low-affinity uptake and efflux of sugar across the membrane; Belongs to the SWEET sugar transporter family.	0.514
RHA2B	SWEET6B-3	A0A2I0V915	A0A2I0VQL5	Putative E3 ubiquitin-protein ligase RHA2B.	Bidirectional sugar transporter SWEET6b.	0.514
RHA2B	SWEET7B-2	A0A2I0V915	A0A2I0VQM2	Putative E3 ubiquitin-protein ligase RHA2B.	Bidirectional sugar transporter SWEET; Mediates both low-affinity uptake and efflux of sugar across the membrane; Belongs to the SWEET sugar transporter family.	0.514
RHA2B	SWEET7B-3	A0A2I0V915	A0A2I0VQN1	Putative E3 ubiquitin-protein ligase RHA2B.	Bidirectional sugar transporter SWEET; Mediates both low-affinity uptake and efflux of sugar across the membrane; Belongs to the SWEET sugar transporter family.	0.514

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Network Stats

number of nodes:

2

number of edges:

1

average node degree:

1

avg. local clustering coefficient:

1

expected number of edges:

1

PPI enrichment p-value:

0.5

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000724

Double-strand break repair via homologous recombination

3 of 4

2.43

1.93

0.00054

GO:0006281

DNA repair

4 of 50

1.46

1.23

0.0020

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003690

Double-stranded DNA binding

3 of 14

1.89

1.25

0.0057

GO:0003678

DNA helicase activity

3 of 14

1.89

1.25

0.0057

GO:0004527

Exonuclease activity

3 of 20

1.73

1.2

0.0057

GO:0016887

ATP hydrolysis activity

3 of 41

1.42

0.86

0.0179

GO:0008408

3-5 exonuclease activity

2 of 9

1.9

0.86

0.0319

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0033202

DNA helicase complex

3 of 8

2.13

2.0

0.00027

GO:1902494

Catalytic complex

4 of 68

1.33

1.21

0.00092

GO:0032991

Protein-containing complex

5 of 170

1.03

0.88

0.0011

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1230

PD-(D/E)XK nuclease superfamily, and CBS domain

4 of 6

2.38

3.11

3.40e-06

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0033202

DNA helicase complex

3 of 13

1.92

1.48

0.0020

GOCC:0044815

DNA packaging complex

3 of 15

1.86

1.46

0.0020

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0269

Exonuclease

3 of 11

1.99

1.9

0.00033

KW-0234

DNA repair

4 of 31

1.67

1.72

0.00024

KW-0227

DNA damage

4 of 31

1.67

1.72

0.00024

KW-0347

Helicase

3 of 20

1.73

1.5

0.0012

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13361

UvrD-like helicase C-terminal domain

3 of 3

2.56

2.31

0.00013

PF12705

PD-(D/E)XK nuclease superfamily

3 of 4

2.43

2.28

0.00013

PF13245

AAA domain

2 of 5

2.16

0.99

0.0212

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR038726

PD-(D/E)XK endonuclease-like domain, AddAB-type

3 of 4

2.43

1.92

0.00058

IPR011604

PD-(D/E)XK endonuclease-like domain superfamily

3 of 4

2.43

1.92

0.00058

IPR011335

Restriction endonuclease type II-like

3 of 7

2.19

1.82

0.00067

IPR014016

UvrD-like helicase, ATP-binding domain

3 of 8

2.13

1.8

0.00068

IPR000212

DNA helicase, UvrD/REP type

3 of 8

2.13

1.8

0.00068

(more ...)

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