STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHL2RNA-dependent RNA polymerase; Probably involved in the RNA silencing pathway and required for the generation of small interfering RNAs (siRNAs). Belongs to the RdRP family. (1182 aa)    
Predicted Functional Partners:
DCL4
Endoribonuclease Dicer like 4; Belongs to the helicase family. Dicer subfamily.
    
 
 0.767
NRPD1
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.757
MA16_Dca011254
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
      
 0.659
DCL3A
Endoribonuclease Dicer like 3a; Belongs to the helicase family. Dicer subfamily.
   
 
 0.581
RH32
RNA helicase.
      
 0.569
MA16_Dca012851
DEAD-box ATP-dependent RNA helicase 17; Belongs to the DEAD box helicase family.
      
 0.569
MA16_Dca026025
RNA helicase.
      
 0.569
HACL
2-hydroxyacyl-CoA lyase.
      
 0.569
HACL-2
2-hydroxyacyl-CoA lyase; Belongs to the TPP enzyme family.
      
 0.569
HB2-2
Non-symbiotic hemoglobin 2; Belongs to the globin family.
      
 0.566
Your Current Organism:
Dendrobium catenatum
NCBI taxonomy Id: 906689
Other names: D. catenatum
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