STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TOP6BDNA topoisomerase 6 subunit B; Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity. The B subunit binds ATP; Belongs to the TOP6B family. (833 aa)    
Predicted Functional Partners:
TOP6A
DNA topoisomerase 6 subunit A; Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
 
 0.967
SPO11-2-2
Meiotic recombination protein SPO11-2.
 
 
 0.906
SPO11-1
Meiotic recombination protein SPO11-1.
 
 
 0.904
SPO11-2
Meiotic recombination protein SPO11-2.
  
 
 0.881
BIN4
DNA-binding protein BIN4.
   
 
 0.672
MA16_Dca025180
S1 motif domain-containing protein.
   
 
 0.637
MA16_Dca022097
Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
   
  
 0.595
MA16_Dca025692
H/ACA ribonucleoprotein complex subunit 3-like protein.
     
 0.574
MA16_Dca001187
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
      
 0.569
MA16_Dca026508
Putative DNA primase large subunit.
      
 0.569
Your Current Organism:
Dendrobium catenatum
NCBI taxonomy Id: 906689
Other names: D. catenatum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.