STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhD-1Dihydrolipoyl dehydrogenase. (454 aa)    
Predicted Functional Partners:
pdhB
Pyruvate dehydrogenase E1 component beta subunit.
 
 0.997
pdhC
Dihydrolipoamide acetyltransferase.
 
 0.997
pdhA
Pyruvate dehydrogenase E1-alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 
 0.994
pdhD
Dihydrolipoamide dehydrogenase.
 
0.992
ADQ90910.1
Hypothetical protein.
    
 0.973
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.918
lplA
Lipoate-protein ligase A.
  
 
 0.876
lplA-1
Lipoate-protein ligase A.
  
 
 0.868
prsA
Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family.
   
 0.729
nagA
N-acetylglucosamine-6-phosphate deacetylase.
     
 0.514
Your Current Organism:
Mycoplasma hyopneumoniae
NCBI taxonomy Id: 907287
Other names: M. hyopneumoniae 168, Mycoplasma hyopneumoniae 168, Mycoplasma hyopneumoniae str. 168, Mycoplasma hyopneumoniae strain 168
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