STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFR31652.1Hydrolase, alpha/beta domain protein; Identified by match to protein family HMM PF07859. (430 aa)    
Predicted Functional Partners:
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
 0.964
EFR31904.1
Putative esterase; Identified by match to protein family HMM PF00756.
    
 0.723
EFR31851.1
Cyclic nucleotide-binding domain protein; Identified by match to protein family HMM PF00027; match to protein family HMM PF00325.
     
 0.674
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 
 0.662
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
   
 
 0.661
EFR31773.1
Identified by match to protein family HMM PF01575.
 
   
 0.654
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
    
   0.651
EFR31908.1
Hypothetical protein.
 
  
 0.648
pdxB
4-phosphoerythronate dehydrogenase; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
  0.631
gcdC
acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Identified by match to protein family HMM PF00364.
    
 0.623
Your Current Organism:
Eremococcus coleocola
NCBI taxonomy Id: 908337
Other names: E. coleocola ACS-139-V-Col8, Eremococcus coleocola ACS-139-V-Col8, Eremococcus coleocola str. ACS-139-V-Col8, Eremococcus coleocola strain ACS-139-V-Col8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.