STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFR31655.1HAD hydrolase, family IA, variant 3; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549. (212 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
  
 
  0.847
EFR31109.1
GMP synthase domain protein; Identified by match to protein family HMM PF00958.
  
 
  0.847
cinA
Competence/damage-inducible domain protein CinA; Identified by match to protein family HMM PF00994; match to protein family HMM PF02464; match to protein family HMM TIGR00199; match to protein family HMM TIGR00200; Belongs to the CinA family.
    
  0.841
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.778
EFR31610.1
HAD hydrolase, family IA, variant 1; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549.
  
 
 0.564
EFR31150.1
Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.
  
 
 0.557
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
  
  0.548
rpsK
30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
   
  0.539
EFR31863.1
HAD hydrolase, family IA, variant 1; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549.
 
 0.502
EFR31665.1
Pyridine nucleotide-disulfide oxidoreductase.
  
    0.500
Your Current Organism:
Eremococcus coleocola
NCBI taxonomy Id: 908337
Other names: E. coleocola ACS-139-V-Col8, Eremococcus coleocola ACS-139-V-Col8, Eremococcus coleocola str. ACS-139-V-Col8, Eremococcus coleocola strain ACS-139-V-Col8
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