STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhB-2Transketolase, pyridine binding domain protein; Identified by match to protein family HMM PF02779; match to protein family HMM PF02780. (325 aa)    
Predicted Functional Partners:
pdhA
Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 0.999
pdhA-2
Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 0.999
bfmBAA
Dehydrogenase E1 component; Identified by match to protein family HMM PF00676.
 0.998
EFR31511.1
2-oxo acid dehydrogenase acyltransferase (catalytic domain); Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.
 0.994
pdhC
2-oxo acid dehydrogenase acyltransferase (catalytic domain); Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.
 0.989
prs
Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.978
lpdA-2
Dihydrolipoyl dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00890; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.
 
 0.976
bfmBB
2-oxo acid dehydrogenase acyltransferase (catalytic domain); Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.
 0.975
lpdA
Dihydrolipoyl dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.
 
 0.942
lpdA-3
Dihydrolipoyl dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.
 
 0.930
Your Current Organism:
Eremococcus coleocola
NCBI taxonomy Id: 908337
Other names: E. coleocola ACS-139-V-Col8, Eremococcus coleocola ACS-139-V-Col8, Eremococcus coleocola str. ACS-139-V-Col8, Eremococcus coleocola strain ACS-139-V-Col8
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