STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepTPeptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. (410 aa)    
Predicted Functional Partners:
gshAB
Glutamate--cysteine ligase/gamma-glutamylcysteine synthetase; This gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF01071; match to protein family HMM PF04262; match to protein family HMM TIGR01435; Belongs to the glutamate--cysteine ligase type 1 family.
  
 
 0.941
EFR31947.1
Dinuclear metal center protein, YbgI family; Identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486.
  
    0.819
EFR32048.1
Identified by match to protein family HMM PF04816.
  
    0.765
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.698
EFR31770.1
Creatinase; Identified by match to protein family HMM PF00557; match to protein family HMM PF01321.
  
 
 0.685
EFR31481.1
Creatinase; Identified by match to protein family HMM PF00557; match to protein family HMM PF01321; Belongs to the peptidase M24B family.
  
 
 0.685
noxE
NADH oxidase; Identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992.
   
 
 0.651
cysK
Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139.
    
 0.620
guaC
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
    
 
 0.602
clpX
ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
  
  
 0.595
Your Current Organism:
Eremococcus coleocola
NCBI taxonomy Id: 908337
Other names: E. coleocola ACS-139-V-Col8, Eremococcus coleocola ACS-139-V-Col8, Eremococcus coleocola str. ACS-139-V-Col8, Eremococcus coleocola strain ACS-139-V-Col8
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