node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ccpA | guaA | HMPREF9257_1040 | HMPREF9257_0399 | Identified by match to protein family HMM PF00356; match to protein family HMM PF00532; match to protein family HMM TIGR01481. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.683 |
ccpA | guaB | HMPREF9257_1040 | HMPREF9257_0759 | Identified by match to protein family HMM PF00356; match to protein family HMM PF00532; match to protein family HMM TIGR01481. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.683 |
ccpA | malX | HMPREF9257_1040 | HMPREF9257_0848 | Identified by match to protein family HMM PF00356; match to protein family HMM PF00532; match to protein family HMM TIGR01481. | PTS system maltose and glucose-specific IIBC component; Identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR02004. | 0.854 |
ccpA | nagE | HMPREF9257_1040 | HMPREF9257_0298 | Identified by match to protein family HMM PF00356; match to protein family HMM PF00532; match to protein family HMM TIGR01481. | PTS system, N-acetylglucosamine-specific IIBC component; Identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR01998. | 0.854 |
ccpA | prs | HMPREF9257_1040 | HMPREF9257_0201 | Identified by match to protein family HMM PF00356; match to protein family HMM PF00532; match to protein family HMM TIGR01481. | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.696 |
ccpA | ptsG | HMPREF9257_1040 | HMPREF9257_0019 | Identified by match to protein family HMM PF00356; match to protein family HMM PF00532; match to protein family HMM TIGR01481. | Phosphotransferase system, EIIC; Identified by match to protein family HMM PF00367; match to protein family HMM PF02378. | 0.854 |
ccpA | ptsH | HMPREF9257_1040 | HMPREF9257_1420 | Identified by match to protein family HMM PF00356; match to protein family HMM PF00532; match to protein family HMM TIGR01481. | Phosphocarrier protein HPr; Identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003. | 0.946 |
ccpA | pyk | HMPREF9257_1040 | HMPREF9257_0950 | Identified by match to protein family HMM PF00356; match to protein family HMM PF00532; match to protein family HMM TIGR01481. | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF00391; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.862 |
ccpA | tkt | HMPREF9257_1040 | HMPREF9257_0287 | Identified by match to protein family HMM PF00356; match to protein family HMM PF00532; match to protein family HMM TIGR01481. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.699 |
ccpA | treP | HMPREF9257_1040 | HMPREF9257_0776 | Identified by match to protein family HMM PF00356; match to protein family HMM PF00532; match to protein family HMM TIGR01481. | PTS system trehalose-specific IIBC component; Identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR01992. | 0.958 |
guaA | ccpA | HMPREF9257_0399 | HMPREF9257_1040 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | Identified by match to protein family HMM PF00356; match to protein family HMM PF00532; match to protein family HMM TIGR01481. | 0.683 |
guaA | guaB | HMPREF9257_0399 | HMPREF9257_0759 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
guaA | prs | HMPREF9257_0399 | HMPREF9257_0201 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.645 |
guaA | pyk | HMPREF9257_0399 | HMPREF9257_0950 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF00391; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.579 |
guaA | tkt | HMPREF9257_0399 | HMPREF9257_0287 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.438 |
guaA | treP | HMPREF9257_0399 | HMPREF9257_0776 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | PTS system trehalose-specific IIBC component; Identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR01992. | 0.536 |
guaB | ccpA | HMPREF9257_0759 | HMPREF9257_1040 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Identified by match to protein family HMM PF00356; match to protein family HMM PF00532; match to protein family HMM TIGR01481. | 0.683 |
guaB | guaA | HMPREF9257_0759 | HMPREF9257_0399 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.999 |
guaB | prs | HMPREF9257_0759 | HMPREF9257_0201 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.708 |
guaB | pyk | HMPREF9257_0759 | HMPREF9257_0950 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF00391; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.769 |