STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ywlELow molecular weight protein-tyrosine-phosphatase YwlE. (148 aa)    
Predicted Functional Partners:
ywlF
Putative sugar phosphate isomerase YwlF.
   
  0.987
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 0.912
cdr_1
Coenzyme A disulfide reductase; Belongs to the sulfur carrier protein TusA family.
   
 
 0.911
ywlC
Threonylcarbamoyl-AMP synthase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
    
  0.906
zupT
Zinc transporter ZupT.
       0.866
KRQ85871.1
Chain length determinant protein.
  
 
 0.849
trxA_1
Thioredoxin.
  
 
 0.809
trxA_2
Thioredoxin; Belongs to the thioredoxin family.
  
 
 0.809
trxA_3
Thioredoxin.
  
 
 0.809
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
       0.774
Your Current Organism:
Caloramator mitchellensis
NCBI taxonomy Id: 908809
Other names: C. mitchellensis, Caloramator mitchellensis Ogg and Patel 2011, Caloramator sp. VF08, JCM 15828, KCTC 5735, strain VF08
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.