STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mleNMalate-2H(+)/Na(+)-lactate antiporter. (471 aa)    
Predicted Functional Partners:
KRQ87386.1
Putative 2-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
    0.465
metK
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
      
 0.434
alsT
Amino-acid carrier protein AlsT.
 
  
 0.427
fruA_1
PTS system fructose-specific EIIBC component.
     
 0.414
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
     
 0.413
ptsG
PTS system glucose-specific EIICB component.
      
 0.408
Your Current Organism:
Caloramator mitchellensis
NCBI taxonomy Id: 908809
Other names: C. mitchellensis, Caloramator mitchellensis Ogg and Patel 2011, Caloramator sp. VF08, JCM 15828, KCTC 5735, strain VF08
Server load: low (14%) [HD]