close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRF4Interferon regulatory factor 4. (445 aa)    
Predicted Functional Partners:
SGK3
Serum/glucocorticoid regulated kinase family member 3.
    
 0.628
TRAF6
TNF receptor associated factor 6.
    
 0.563
IRF1
Interferon regulatory factor 1.
   
0.497
MYD88
MYD88 innate immune signal transduction adaptor.
   
 0.484
SPI1
Spi-1 proto-oncogene.
   
 
 0.476
AKT1
AKT serine/threonine kinase 1.
    
 0.467
AKT3
AKT serine/threonine kinase 3.
    
 0.467
EP300
E1A binding protein p300.
    
 0.465
SIRT1
Sirtuin 1.
    
 0.464
SIRT5
Sirtuin 5.
    
 0.464
Your Current Organism:
Chrysolophus pictus
NCBI taxonomy Id: 9089
Other names: C. pictus, golden pheasant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.