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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACER1Alkaline ceramidase 1. (263 aa)    
Predicted Functional Partners:
SMPD2
Sphingomyelin phosphodiesterase 2.
    
 0.971
ENSCPIP00010016008
annotation not available
    
 0.968
GBA2
Glucosylceramidase beta 2.
     
 0.965
SGMS2
Sphingomyelin synthase 2.
     
 0.964
CERK
Ceramide kinase.
    
 0.959
ASAH1
N-acylsphingosine amidohydrolase 1.
     
 0.959
SMPD1
Sphingomyelin phosphodiesterase 1.
     
 0.950
UGCG
UDP-glucose ceramide glucosyltransferase.
     
 0.947
SGMS1
Sphingomyelin synthase 1.
     
 0.946
ENSCPIP00010008326
annotation not available
    
 0.943
Your Current Organism:
Chrysolophus pictus
NCBI taxonomy Id: 9089
Other names: C. pictus, golden pheasant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.