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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHPRHSNF2 histone linker PHD RING helicase. (1550 aa)    
Predicted Functional Partners:
RAD18
RAD18 E3 ubiquitin protein ligase.
    
 0.957
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 0.941
UBE2V2
Ubiquitin conjugating enzyme E2 V2.
    
 0.831
FANCM
FA complementation group M.
    
 0.825
MYSM1
Myb like, SWIRM and MPN domains 1.
   
 0.824
UBE2V1
Ubiquitin conjugating enzyme E2 V1.
    
 0.820
ENSCPIP00010015073
annotation not available
    
 0.792
WRN
WRN RecQ like helicase.
  
 
 0.736
PCNA
Proliferating cell nuclear antigen.
   
 0.711
FOXN2
Forkhead box N2.
    
 
 0.668
Your Current Organism:
Chrysolophus pictus
NCBI taxonomy Id: 9089
Other names: C. pictus, golden pheasant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.