Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPRY2Sprouty RTK signaling antagonist 2. (313 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.995
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
    
 0.967
CBL
Cbl proto-oncogene.
    
 0.965
CBLB
Cbl proto-oncogene B.
    
 0.965
ENSCPIP00010004314
annotation not available
     
  0.889
SPRY1
Sprouty RTK signaling antagonist 1.
   
  0.823
GRAP2
GRB2 related adaptor protein 2.
    
  0.744
ENSCPIP00010016413
annotation not available
    
  0.744
RASA2
RAS p21 protein activator 2.
    
  0.729
RASA3
RAS p21 protein activator 3.
    
  0.729
Your Current Organism:
Chrysolophus pictus
NCBI taxonomy Id: 9089
Other names: C. pictus, golden pheasant
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