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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARRDC4Arrestin domain containing 4. (310 aa)    
Predicted Functional Partners:
NEDD4L
NEDD4 like E3 ubiquitin protein ligase.
    
 
 0.637
NEDD4
NEDD4 E3 ubiquitin protein ligase.
    
 
 0.637
TXN2
Thioredoxin 2.
    
 0.597
POLR2D
RNA polymerase II subunit D.
      
 0.592
ENSCPIP00010015510
annotation not available
      
 0.583
SLC25A28
Solute carrier family 25 member 28.
      
 0.581
EME2
Essential meiotic structure-specific endonuclease subunit 2.
      
 0.545
EMC3
ER membrane protein complex subunit 3.
      
 0.537
ENSCPIP00010011801
annotation not available
      
 0.537
SLCO4A1
Solute carrier organic anion transporter family member 4A1.
      
 0.534
Your Current Organism:
Chrysolophus pictus
NCBI taxonomy Id: 9089
Other names: C. pictus, golden pheasant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.