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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAK1P21 (RAC1) activated kinase 1. (544 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
   
 0.994
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.979
NCK2
NCK adaptor protein 2.
    
 0.972
ARHGEF7
Rho guanine nucleotide exchange factor 7.
    
 0.966
RAC3
Rac family small GTPase 3.
    
 0.956
RAC1
Rac family small GTPase 1.
    
 0.956
ITSN2
Intersectin 2.
    
 0.953
RAC2
Rac family small GTPase 2.
    
 0.953
ENSCPIP00010000182
annotation not available
    
0.940
MAP3K3
Mitogen-activated protein kinase kinase kinase 3.
    
0.940
Your Current Organism:
Chrysolophus pictus
NCBI taxonomy Id: 9089
Other names: C. pictus, golden pheasant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.