close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MKNK2MAPK interacting serine/threonine kinase 2. (129 aa)    
Predicted Functional Partners:
MAPK1
Mitogen-activated protein kinase 1.
    
 0.949
EIF4E
Eukaryotic translation initiation factor 4E.
    
 0.946
MAPK7
Mitogen-activated protein kinase 7.
    
 0.919
ATF4
Activating transcription factor 4.
     
 0.915
MKNK1
MAPK interacting serine/threonine kinase 1.
  
  
 
0.914
EIF4E3
Eukaryotic translation initiation factor 4E family member 3.
    
 0.668
SH3D19
SH3 domain containing 19.
      
 0.577
MAPK14
Mitogen-activated protein kinase 14.
   
 0.567
MAPK11
Mitogen-activated protein kinase 11.
   
 0.567
MFSD2B
Major facilitator superfamily domain containing 2B.
      
 0.560
Your Current Organism:
Chrysolophus pictus
NCBI taxonomy Id: 9089
Other names: C. pictus, golden pheasant
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.