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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDIA4Protein disulfide isomerase family A member 4. (509 aa)    
Predicted Functional Partners:
PDIA6
Protein disulfide isomerase family A member 6.
   
0.984
ERO1B
Endoplasmic reticulum oxidoreductase 1 beta.
   
 0.969
ERO1A
Endoplasmic reticulum oxidoreductase 1 alpha.
   
 0.968
HYOU1
Hypoxia up-regulated 1.
  
 0.964
HSPA5
Heat shock protein family A (Hsp70) member 5.
  
 0.959
DNAJC10
DnaJ heat shock protein family (Hsp40) member C10.
   
0.955
TXNDC5
Thioredoxin domain containing 5.
   
0.952
CALR
Calreticulin.
   
 0.941
HSP90B1
Heat shock protein 90 beta family member 1.
  
 0.935
ENSCPIP00010010382
annotation not available
    
 0.903
Your Current Organism:
Chrysolophus pictus
NCBI taxonomy Id: 9089
Other names: C. pictus, golden pheasant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.