close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPN11Protein tyrosine phosphatase non-receptor type 11. (593 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
   
0.992
PECAM1
Platelet and endothelial cell adhesion molecule 1.
   
 0.978
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
    
 0.970
JAK2
Janus kinase 2.
   
 0.959
GAB1
GRB2 associated binding protein 1.
    
 0.959
SYK
Spleen associated tyrosine kinase.
   
0.950
RUNX2
RUNX family transcription factor 2.
   
 
 0.949
SHC1
SHC adaptor protein 1.
   
 0.947
ENSCPIP00010007164
annotation not available
  
  
 
0.919
IRS1
Insulin receptor substrate 1.
    
 0.911
Your Current Organism:
Chrysolophus pictus
NCBI taxonomy Id: 9089
Other names: C. pictus, golden pheasant
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