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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMPDL3ASphingomyelin phosphodiesterase acid like 3A. (360 aa)    
Predicted Functional Partners:
SHISAL1
Shisa like 1.
      
 0.594
CEP104
Centrosomal protein 104.
      
 0.557
ERCC6L
ERCC excision repair 6 like, spindle assembly checkpoint helicase.
      
 0.545
LLGL2
LLGL scribble cell polarity complex component 2.
      
 0.537
DNASE1L3
Deoxyribonuclease 1 like 3.
      
 0.535
ENSCPIP00010018220
annotation not available
      
 0.530
BRINP1
BMP/retinoic acid inducible neural specific 1.
      
 0.529
NPC2
NPC intracellular cholesterol transporter 2.
   
 
  0.529
ENSCPIP00010017981
annotation not available
      
 0.463
CEMIP2
Cell migration inducing hyaluronidase 2.
      
 0.457
Your Current Organism:
Chrysolophus pictus
NCBI taxonomy Id: 9089
Other names: C. pictus, golden pheasant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.