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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRB10Growth factor receptor bound protein 10. (596 aa)    
Predicted Functional Partners:
IGF1R
Insulin like growth factor 1 receptor.
    
 0.950
INSR
Insulin receptor.
    
 0.950
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
  0.942
PIK3CA
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.
    
 0.929
MTOR
Mechanistic target of rapamycin kinase.
     
 0.919
MST1R
Macrophage stimulating 1 receptor.
   
 0.653
RASGRF1
Ras protein specific guanine nucleotide releasing factor 1.
    
 0.650
MET
MET proto-oncogene, receptor tyrosine kinase.
    
 0.649
DLK1
Delta like non-canonical Notch ligand 1.
   
 0.640
CRK
CRK proto-oncogene, adaptor protein.
    
 0.618
Your Current Organism:
Chrysolophus pictus
NCBI taxonomy Id: 9089
Other names: C. pictus, golden pheasant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.