STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UO65_1168Octaprenyl-diphosphate synthase; Dimethylallyltransferase; Geranyltranstransferase (farnesyldiphosphate synthase); Geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. (338 aa)    
Predicted Functional Partners:
UO65_5889
Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.972
UO65_6503
Phytoene synthase.
  
 0.966
UO65_5554
Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.922
UO65_6501
Dimethylallyltransferase; (2E,6E)-farnesyl diphosphate synthase; Farnesyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
  
 
0.903
idi
Isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
  
 
 0.882
UO65_4484
Germacradienol synthase.
 
   
 0.872
UO65_6608
Octaprenyl diphosphate synthase; Dimethylallyltransferase; Geranyltranstransferase; Geranylgeranyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
  
  
 
0.794
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
  
 
 0.791
UO65_1736
Geranylgeranyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
  
  
 
0.786
UO65_0179
Octaprenyl diphosphate synthase; Dimethylallyltransferase; (2E,6E)-farnesyl diphosphate synthase; Geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family.
  
  
 
0.782
Your Current Organism:
Actinokineospora spheciospongiae
NCBI taxonomy Id: 909613
Other names: A. spheciospongiae, Actinokineospora sp. EG49, Actinokineospora spheciospongiae Kampfer et al. 2015 emend. Nouioui et al. 2018, CCM 8480, DSM 45935, LMG 27700, LMG:27700, strain EG49
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