STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UO65_1753Pup ligase PafA. (502 aa)    
Predicted Functional Partners:
arc
Bacterial proteasome-activating AAA-ATPase (PAN).
  
 0.935
prcB
Proteasome subunit beta, bacterial; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.
 
   
 0.934
pup
Prokaryotic ubiquitin-like protein Pup; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation. Belongs to the prokaryotic ubiquitin-like protein family.
 
  
 0.931
prcA
Proteasome subunit alpha, bacterial; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.
   
 0.928
UO65_4556
Hypothetical protein; FIG00819990.
  
     0.645
UO65_2966
Hypothetical protein; FIG00822472.
  
   
 0.622
UO65_3290
Hypothetical protein; FIG00819990.
  
     0.595
UO65_0800
Polyketide synthase.
  
 0.590
UO65_1871
Non-ribosomal peptide synthetase.
  
 0.590
UO65_4804
Transcriptional regulator, MerR family.
  
     0.574
Your Current Organism:
Actinokineospora spheciospongiae
NCBI taxonomy Id: 909613
Other names: A. spheciospongiae, Actinokineospora sp. EG49, Actinokineospora spheciospongiae Kampfer et al. 2015 emend. Nouioui et al. 2018, CCM 8480, DSM 45935, LMG 27700, LMG:27700, strain EG49
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