STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UO65_4420Acetoin dehydrogenase E1 component beta-subunit. (327 aa)    
Predicted Functional Partners:
UO65_3195
Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; 2-oxoglutarate dehydrogenase E1 component.
 
 0.999
UO65_4421
Pyruvate dehydrogenase E1 component alpha subunit.
 0.999
UO65_6365
Pyruvate dehydrogenase E1 component alpha subunit.
 0.999
UO65_6363
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 0.997
UO65_3280
Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex.
 0.992
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.987
UO65_3279
Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase.
 0.984
UO65_3137
Dihydrolipoamide dehydrogenase.
 0.981
UO65_0198
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.980
UO65_4029
Dihydrolipoamide dehydrogenase.
 0.967
Your Current Organism:
Actinokineospora spheciospongiae
NCBI taxonomy Id: 909613
Other names: A. spheciospongiae, Actinokineospora sp. EG49, Actinokineospora spheciospongiae Kampfer et al. 2015 emend. Nouioui et al. 2018, CCM 8480, DSM 45935, LMG 27700, LMG:27700, strain EG49
Server load: low (16%) [HD]