STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UO65_44334-hydroxyphenylpyruvate dioxygenase. (339 aa)    
Predicted Functional Partners:
UO65_1818
Homogentisate 1,2-dioxygenase.
 
 0.986
UO65_6459
Methylcrotonyl-CoA carboxylase biotin-containing subunit.
  
 
 0.900
UO65_1816
Fumarylacetoacetase.
 
  
 0.886
UO65_4432
Phytanoyl-CoA dioxygenase.
     0.860
UO65_4252
Ethylmalonyl-CoA mutase, methylsuccinyl-CoA-forming.
    
 0.832
icmF
B12 binding domain; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
    
 0.816
UO65_4441
L-lactate dehydrogenase.
 
 
 0.816
UO65_0953
Biotin carboxylase.
  
 
 0.775
UO65_4692
Malonyl CoA-acyl carrier protein transacylase.
    
 0.767
UO65_0800
Polyketide synthase.
    
 0.763
Your Current Organism:
Actinokineospora spheciospongiae
NCBI taxonomy Id: 909613
Other names: A. spheciospongiae, Actinokineospora sp. EG49, Actinokineospora spheciospongiae Kampfer et al. 2015 emend. Nouioui et al. 2018, CCM 8480, DSM 45935, LMG 27700, LMG:27700, strain EG49
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