STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UO65_4505Isochorismatase hydrolase. (198 aa)    
Predicted Functional Partners:
UO65_4504
Transcriptional regulator, AraC family.
    0.949
UO65_4470
Isochorismatase.
  
  
  0.784
UO65_0794
Hypothetical protein; FIG01135360.
  
  
  0.779
UO65_0786
Isochorismatase of siderophore biosynthesis.
  
  
 0.597
UO65_5571
Isochorismatase.
  
  
  0.597
UO65_5722
Xanthine dehydrogenase, molybdenum binding subunit.
    
  0.566
UO65_3933
Transcriptional regulator, AraC family.
    0.527
UO65_0800
Polyketide synthase.
  
 
 0.513
UO65_1871
Non-ribosomal peptide synthetase.
  
 
 0.513
nnrE
NAD(P)HX epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epime [...]
   
    0.478
Your Current Organism:
Actinokineospora spheciospongiae
NCBI taxonomy Id: 909613
Other names: A. spheciospongiae, Actinokineospora sp. EG49, Actinokineospora spheciospongiae Kampfer et al. 2015 emend. Nouioui et al. 2018, CCM 8480, DSM 45935, LMG 27700, LMG:27700, strain EG49
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