STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UO65_4586Putative glyoxylase. (123 aa)    
Predicted Functional Partners:
UO65_4252
Ethylmalonyl-CoA mutase, methylsuccinyl-CoA-forming.
    
 0.773
UO65_1172
2-oxoglutarate oxidoreductase, alpha subunit.
     
 0.719
icmF
B12 binding domain; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
    
 0.630
UO65_4692
Malonyl CoA-acyl carrier protein transacylase.
  
 0.587
UO65_6459
Methylcrotonyl-CoA carboxylase biotin-containing subunit.
  
 
 0.585
nuoI
NADH-ubiquinone oxidoreductase chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 
 0.577
UO65_0953
Biotin carboxylase.
  
 
 0.571
UO65_4021
Methylmalonyl-CoA mutase.
    
 0.569
UO65_4022
Methylmalonyl-CoA mutase.
    
 0.569
UO65_4587
RNA 3'-terminal phosphate cyclase.
       0.560
Your Current Organism:
Actinokineospora spheciospongiae
NCBI taxonomy Id: 909613
Other names: A. spheciospongiae, Actinokineospora sp. EG49, Actinokineospora spheciospongiae Kampfer et al. 2015 emend. Nouioui et al. 2018, CCM 8480, DSM 45935, LMG 27700, LMG:27700, strain EG49
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