STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coaEDephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (394 aa)    
Predicted Functional Partners:
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
    
 0.978
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
    0.898
UO65_3131
Modular polyketide synthase.
  
 
 0.891
UO65_4692
Malonyl CoA-acyl carrier protein transacylase.
  
 
 0.876
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
  
 0.867
UO65_0407
Methylaspartate mutase, E subunit.
    
 0.827
UO65_3515
Malonyl CoA-acyl carrier protein transacylase.
    
 0.827
UO65_3665
Malonyl CoA-acyl carrier protein transacylase.
    
 0.827
UO65_5306
Malonyl CoA-acyl carrier protein transacylase.
    
 0.827
UO65_6650
Malonyl CoA-acyl carrier protein transacylase.
    
 0.827
Your Current Organism:
Actinokineospora spheciospongiae
NCBI taxonomy Id: 909613
Other names: A. spheciospongiae, Actinokineospora sp. EG49, Actinokineospora spheciospongiae Kampfer et al. 2015 emend. Nouioui et al. 2018, CCM 8480, DSM 45935, LMG 27700, LMG:27700, strain EG49
Server load: low (24%) [HD]