STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UO65_5248Hypothetical protein. (151 aa)    
Predicted Functional Partners:
UO65_3557
Phenylacetate-coenzyme A ligase.
  
 
 0.714
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
       0.530
UO65_4088
Phosphohydrolase (MutT/nudix family protein).
  
 
  0.516
UO65_4232
Hypothetical protein; FIG01125674.
  
 
 0.513
UO65_0907
Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.
  
 
  0.508
UO65_3235
Phenylacetate-CoA oxygenase/reductase, PaaK subunit.
  
 
  0.508
UO65_3587
Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; Vanillate O-demethylase oxidoreductase.
  
 
  0.508
UO65_4858
Phenylacetate-CoA oxygenase/reductase, PaaK subunit.
  
 
  0.508
UO65_5620
Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.
  
 
  0.508
UO65_6046
Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.
  
 
  0.508
Your Current Organism:
Actinokineospora spheciospongiae
NCBI taxonomy Id: 909613
Other names: A. spheciospongiae, Actinokineospora sp. EG49, Actinokineospora spheciospongiae Kampfer et al. 2015 emend. Nouioui et al. 2018, CCM 8480, DSM 45935, LMG 27700, LMG:27700, strain EG49
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