| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EHI48070.1 | EHI48084.1 | HIMB100_00016450 | HIMB100_00016590 | PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase. | Indolepyruvate ferredoxin oxidreductase, alpha/beta subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | 0.751 |
| EHI48070.1 | EHI48436.1 | HIMB100_00016450 | HIMB100_00020200 | PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase. | PFAM: Malic enzyme, NAD binding domain; Phosphate acetyl/butaryl transferase; Malic enzyme, N-terminal domain. | 0.713 |
| EHI48070.1 | EHI49329.1 | HIMB100_00016450 | HIMB100_00008990 | PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase. | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.752 |
| EHI48070.1 | EHI49475.1 | HIMB100_00016450 | HIMB100_00004360 | PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase. | acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family. | 0.760 |
| EHI48070.1 | EHI49887.1 | HIMB100_00016450 | HIMB100_00001720 | PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase. | Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.696 |
| EHI48070.1 | acsA | HIMB100_00016450 | HIMB100_00018300 | PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.764 |
| EHI48070.1 | glcB | HIMB100_00016450 | HIMB100_00019520 | PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase. | Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.721 |
| EHI48084.1 | EHI48070.1 | HIMB100_00016590 | HIMB100_00016450 | Indolepyruvate ferredoxin oxidreductase, alpha/beta subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase. | 0.751 |
| EHI48084.1 | EHI48436.1 | HIMB100_00016590 | HIMB100_00020200 | Indolepyruvate ferredoxin oxidreductase, alpha/beta subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | PFAM: Malic enzyme, NAD binding domain; Phosphate acetyl/butaryl transferase; Malic enzyme, N-terminal domain. | 0.878 |
| EHI48084.1 | EHI48964.1 | HIMB100_00016590 | HIMB100_00010970 | Indolepyruvate ferredoxin oxidreductase, alpha/beta subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family. | 0.492 |
| EHI48084.1 | EHI49329.1 | HIMB100_00016590 | HIMB100_00008990 | Indolepyruvate ferredoxin oxidreductase, alpha/beta subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.592 |
| EHI48084.1 | EHI49475.1 | HIMB100_00016590 | HIMB100_00004360 | Indolepyruvate ferredoxin oxidreductase, alpha/beta subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family. | 0.851 |
| EHI48084.1 | EHI49887.1 | HIMB100_00016590 | HIMB100_00001720 | Indolepyruvate ferredoxin oxidreductase, alpha/beta subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.842 |
| EHI48084.1 | acsA | HIMB100_00016590 | HIMB100_00018300 | Indolepyruvate ferredoxin oxidreductase, alpha/beta subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.837 |
| EHI48084.1 | glcB | HIMB100_00016590 | HIMB100_00019520 | Indolepyruvate ferredoxin oxidreductase, alpha/beta subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.571 |
| EHI48084.1 | pdhA | HIMB100_00016590 | HIMB100_00001710 | Indolepyruvate ferredoxin oxidreductase, alpha/beta subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.584 |
| EHI48084.1 | sucC | HIMB100_00016590 | HIMB100_00018790 | Indolepyruvate ferredoxin oxidreductase, alpha/beta subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.874 |
| EHI48436.1 | EHI48070.1 | HIMB100_00020200 | HIMB100_00016450 | PFAM: Malic enzyme, NAD binding domain; Phosphate acetyl/butaryl transferase; Malic enzyme, N-terminal domain. | PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase. | 0.713 |
| EHI48436.1 | EHI48084.1 | HIMB100_00020200 | HIMB100_00016590 | PFAM: Malic enzyme, NAD binding domain; Phosphate acetyl/butaryl transferase; Malic enzyme, N-terminal domain. | Indolepyruvate ferredoxin oxidreductase, alpha/beta subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | 0.878 |
| EHI48436.1 | EHI48964.1 | HIMB100_00020200 | HIMB100_00010970 | PFAM: Malic enzyme, NAD binding domain; Phosphate acetyl/butaryl transferase; Malic enzyme, N-terminal domain. | PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family. | 0.884 |
