EHI48666.1 protein (SAR116 cluster) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

SAR116 cluster

NCBI taxonomy Id: 909943
Other names: S. cluster alpha proteobacterium HIMB100, SAR116 cluster alpha proteobacterium HIMB100

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EHI48080.1	EHI48084.1	HIMB100_00016550	HIMB100_00016590	PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.	Indolepyruvate ferredoxin oxidreductase, alpha/beta subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.	0.723
EHI48080.1	EHI48436.1	HIMB100_00016550	HIMB100_00020200	PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.	PFAM: Malic enzyme, NAD binding domain; Phosphate acetyl/butaryl transferase; Malic enzyme, N-terminal domain.	0.829
EHI48080.1	EHI48640.1	HIMB100_00016550	HIMB100_00022250	PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.	PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family.	0.890
EHI48080.1	EHI48666.1	HIMB100_00016550	HIMB100_00022510	PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.	acyl-CoA synthetase/AMP-acid ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme.	0.703
EHI48080.1	EHI49474.1	HIMB100_00016550	HIMB100_00004350	PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.	PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.	0.872
EHI48080.1	EHI49887.1	HIMB100_00016550	HIMB100_00001720	PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.789
EHI48080.1	dnaK	HIMB100_00016550	HIMB100_00020120	PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.460
EHI48080.1	lcdH	HIMB100_00016550	HIMB100_00014770	PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.	3-hydroxyacyl-CoA dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine.	0.898
EHI48084.1	EHI48080.1	HIMB100_00016590	HIMB100_00016550	Indolepyruvate ferredoxin oxidreductase, alpha/beta subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.	PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.	0.723
EHI48084.1	EHI48436.1	HIMB100_00016590	HIMB100_00020200	Indolepyruvate ferredoxin oxidreductase, alpha/beta subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.	PFAM: Malic enzyme, NAD binding domain; Phosphate acetyl/butaryl transferase; Malic enzyme, N-terminal domain.	0.878
EHI48084.1	EHI48640.1	HIMB100_00016590	HIMB100_00022250	Indolepyruvate ferredoxin oxidreductase, alpha/beta subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.	PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family.	0.768
EHI48084.1	EHI48666.1	HIMB100_00016590	HIMB100_00022510	Indolepyruvate ferredoxin oxidreductase, alpha/beta subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.	acyl-CoA synthetase/AMP-acid ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme.	0.837
EHI48084.1	EHI49474.1	HIMB100_00016590	HIMB100_00004350	Indolepyruvate ferredoxin oxidreductase, alpha/beta subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.	PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.	0.549
EHI48084.1	EHI49887.1	HIMB100_00016590	HIMB100_00001720	Indolepyruvate ferredoxin oxidreductase, alpha/beta subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.842
EHI48084.1	dnaK	HIMB100_00016590	HIMB100_00020120	Indolepyruvate ferredoxin oxidreductase, alpha/beta subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.407
EHI48084.1	glcB	HIMB100_00016590	HIMB100_00019520	Indolepyruvate ferredoxin oxidreductase, alpha/beta subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.	Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.	0.571
EHI48084.1	lcdH	HIMB100_00016590	HIMB100_00014770	Indolepyruvate ferredoxin oxidreductase, alpha/beta subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.	3-hydroxyacyl-CoA dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine.	0.562
EHI48436.1	EHI48080.1	HIMB100_00020200	HIMB100_00016550	PFAM: Malic enzyme, NAD binding domain; Phosphate acetyl/butaryl transferase; Malic enzyme, N-terminal domain.	PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.	0.829
EHI48436.1	EHI48084.1	HIMB100_00020200	HIMB100_00016590	PFAM: Malic enzyme, NAD binding domain; Phosphate acetyl/butaryl transferase; Malic enzyme, N-terminal domain.	Indolepyruvate ferredoxin oxidreductase, alpha/beta subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.	0.878
EHI48436.1	EHI48640.1	HIMB100_00020200	HIMB100_00022250	PFAM: Malic enzyme, NAD binding domain; Phosphate acetyl/butaryl transferase; Malic enzyme, N-terminal domain.	PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family.	0.835