GCA_000380925_00071 protein (Atribacteria bacterium SCGC AAA252M02)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

GCA_000380925_00071

Unannotated protein. (177 aa)

Predicted Functional Partners:

GCA_000380925_01748

0.980

GCA_000380925_00070

0.971

GCA_000380925_00982

0.912

GCA_000380925_01638

0.912

GCA_000380925_01975

0.898

GCA_000380925_01913

0.866

GCA_000380925_01745

0.840

GCA_000380925_01818

0.840

GCA_000380925_01817

0.752

GCA_000380925_00246

0.717

Your Current Organism:

Atribacteria bacterium SCGC AAA252M02

NCBI taxonomy Id: 913317
Other names: A. bacterium SCGC AAA252-M02, Atribacteria bacterium SCGC AAA252-M02, candidate division OP9 bacterium SCGC AAA252-M02, candidate division OP9_JS1 bacterium SCGC AAA252-M02

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structured XML interaction data, according to the 'PSI-MI' data standard

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MFA: multi-fasta format - containing the aminoacid sequences in the network

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... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
GCA_000380925_00070	GCA_000380925_00071	Unannotated protein.	Unannotated protein.	0.971
GCA_000380925_00071	GCA_000380925_00070	Unannotated protein.	Unannotated protein.	0.971
GCA_000380925_00071	GCA_000380925_00246	Unannotated protein.	Unannotated protein.	0.717
GCA_000380925_00071	GCA_000380925_00982	Unannotated protein.	Unannotated protein.	0.912
GCA_000380925_00071	GCA_000380925_01638	Unannotated protein.	Unannotated protein.	0.912
GCA_000380925_00071	GCA_000380925_01745	Unannotated protein.	Unannotated protein.	0.840
GCA_000380925_00071	GCA_000380925_01748	Unannotated protein.	Unannotated protein.	0.980
GCA_000380925_00071	GCA_000380925_01817	Unannotated protein.	Unannotated protein.	0.752
GCA_000380925_00071	GCA_000380925_01818	Unannotated protein.	Unannotated protein.	0.840
GCA_000380925_00071	GCA_000380925_01913	Unannotated protein.	Unannotated protein.	0.866
GCA_000380925_00071	GCA_000380925_01975	Unannotated protein.	Unannotated protein.	0.898
GCA_000380925_00246	GCA_000380925_00071	Unannotated protein.	Unannotated protein.	0.717
GCA_000380925_00246	GCA_000380925_01745	Unannotated protein.	Unannotated protein.	0.871
GCA_000380925_00246	GCA_000380925_01818	Unannotated protein.	Unannotated protein.	0.875
GCA_000380925_00246	GCA_000380925_01913	Unannotated protein.	Unannotated protein.	0.438
GCA_000380925_00982	GCA_000380925_00071	Unannotated protein.	Unannotated protein.	0.912
GCA_000380925_01638	GCA_000380925_00071	Unannotated protein.	Unannotated protein.	0.912
GCA_000380925_01745	GCA_000380925_00071	Unannotated protein.	Unannotated protein.	0.840
GCA_000380925_01745	GCA_000380925_00246	Unannotated protein.	Unannotated protein.	0.871
GCA_000380925_01745	GCA_000380925_01748	Unannotated protein.	Unannotated protein.	0.422

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

42

average node degree:

7.64

avg. local clustering coefficient:

0.803

expected number of edges:

11

PPI enrichment p-value:

3.1e-12

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005976

Polysaccharide metabolic process

8 of 71

1.73

3.34

4.03e-10

GO:0000271

Polysaccharide biosynthetic process

6 of 65

1.65

2.35

7.59e-07

GO:0016051

Carbohydrate biosynthetic process

7 of 97

1.54

2.32

1.40e-07

GO:0033692

Cellular polysaccharide biosynthetic process

5 of 47

1.71

2.12

9.80e-06

GO:0005975

Carbohydrate metabolic process

9 of 237

1.26

1.78

3.28e-08

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008767

UDP-galactopyranose mutase activity

2 of 2

2.68

0.93

0.0210

GO:0016740

Transferase activity

8 of 832

0.66

0.43

0.0210

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:5129

O-Antigen nucleotide sugar biosynthesis, and Glycosyl transferases group 1

8 of 28

2.14

5.64

4.67e-14

CL:5130

O-Antigen nucleotide sugar biosynthesis

7 of 23

2.16

5.09

3.32e-12

CL:5119

Amino sugar and nucleotide sugar metabolism, and Polysaccharide biosynthetic process

10 of 83

1.76

4.43

3.57e-15

CL:5117

Amino sugar and nucleotide sugar metabolism, and Polysaccharide biosynthetic process

11 of 101

1.72

4.4

2.67e-16

CL:5158

Mannose-6-phosphate isomerase, and NAD dependent epimerase/dehydratase family

3 of 6

2.38

2.29

4.59e-05

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00541

O-Antigen nucleotide sugar biosynthesis

5 of 44

1.74

2.31

3.15e-06

map00520

Amino sugar and nucleotide sugar metabolism

4 of 68

1.45

1.3

0.00062

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0548

Nucleotidyltransferase

3 of 60

1.38

0.69

0.0329

KW-0808

Transferase

7 of 695

0.68

0.41

0.0329

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