Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TIE1Tyrosine-protein kinase receptor Tie-1 isoform X2. (1124 aa)    
Predicted Functional Partners:
TEK
TEK receptor tyrosine kinase.
   
 
 0.961
MUSK
Muscle associated receptor tyrosine kinase.
   
  0.931
ANGPT2
Angiopoietin-2 isoform X1.
   
 0.894
PDGFC
Platelet derived growth factor C/D.
    
 
 0.850
ANGPT1
Angiopoietin 1.
   
 0.826
ANGPT4
Angiopoietin-4 isoform X1.
   
 0.826
CDH5
Cadherin 5, type 2, VE-cadherin.
   
 0.708
KLHL6
Kelch-like protein 6.
   
  
 0.701
GRB2
Growth factor receptor-binding protein 2.
    
 0.687
DOK2
LOW QUALITY PROTEIN: docking protein 2.
    
 0.684
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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