Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CDC20Cell division cycle 20, cofactor of APC complex. (503 aa)    
Predicted Functional Partners:
MAD2L1
Mitotic spindle assembly checkpoint protein MAD2A.
   
 0.999
PLK1
Polo like kinase 1.
   
 0.999
PTTG1
Securin.
   
 0.999
BUB1B
Uncharacterized protein LOC108964006.
   
 0.999
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.999
CCNB2
G2/mitotic-specific cyclin-B2.
   
 0.999
CDK1
Cyclin-dependent kinase 1.
   
 0.998
CCNA2
Cyclin-A2.
   
 0.997
BUB3
Mitotic checkpoint protein BUB3.
   
 0.997
UBE2C
Ubiquitin-conjugating enzyme E2 C.
   
 0.997
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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