Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSSCAP00000001022annotation not available (959 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor-binding protein 2.
   
 0.904
SHC1
SHC-transforming protein 1 isoform X3.
    
 0.783
SHC3
SHC adaptor protein 3.
    
 0.783
ENSSCAP00000007313
annotation not available
    
 0.757
GRAP2
GRB2-related adapter protein 2.
   
 0.756
GRAP
GRB2-related adapter protein isoform X1.
   
 0.746
EPHA2
Ephrin type-A receptor 2.
    
 0.734
CBL
E3 ubiquitin-protein ligase CBL.
    
 0.662
CBLB
E3 ubiquitin-protein ligase CBL-B isoform X1.
    
 0.662
APPL1
DCC-interacting protein 13-alpha isoform X1.
   
 
 0.635
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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