Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TPMTThiopurine S-methyltransferase isoform X2. (254 aa)    
Predicted Functional Partners:
ITPA
Inosine triphosphate pyrophosphatase.
   
 0.954
GMPS
GMP synthase (glutamine-hydrolysing).
  
 
 0.928
HPRT1
Hypoxanthine-guanine phosphoribosyltransferase.
    
 0.927
IMPDH2
Inosine monophosphate dehydrogenase 2.
   
 0.925
ENSSCAP00000004836
Hypoxanthine-guanine phosphoribosyltransferase-like.
    
 0.921
XDH
Xanthine dehydrogenase/oxidase.
     
 0.913
SLC19A1
Solute carrier family 19 member 1.
      
 0.702
ENSSCAP00000023207
Transmembrane O-methyltransferase homolog.
    
 0.701
GGH
Gamma-glutamyl hydrolase.
      
 0.695
NUDT15
Nucleotide triphosphate diphosphatase NUDT15.
      
 0.684
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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